Destroy All Humans! 2

Destroy All Humans! 2 for PlayStation 2 is a 2006 action-adventure game developed by Pandemic Studios and published by THQ. It continues the alien-invasion satire of the first Destroy All Humans!, moving the series from its 1950s backdrop into a deliberately exaggerated 1969 of Cold War anxiety, psychedelic fashion, spy-film clichés, and science-fiction spoofs. Players again control Furon invader Cryptosporidium, known as Crypto, whose mission combines retaliation, reconnaissance, and the Furon Empire’s continuing search for human DNA.

The PlayStation 2 game is built around third-person action across sizeable locations where Crypto can approach objectives with a mix of weaponry, psychic powers, movement, and disguise. On foot, he can use his jetpack to cross rooftops and obstacles, attack soldiers and civilians with alien arms, and employ psychokinesis to lift, throw, or otherwise manipulate people and objects. Some encounters reward direct destruction, while others make better use of infiltration and situational powers. The result is a mission structure that shifts between combat, exploration, sabotage, and comic set pieces.

A central new ability is body snatching, which lets Crypto take a human form to move through guarded areas or fulfill objectives while concealing his identity. His mental abilities also play into the game’s irreverent tone: Free Love can distract nearby humans with an impromptu dance, and Mind Flash can disrupt witnesses. The alien arsenal expands as play progresses, with additional tools recovered through the story, while upgrades are tied to the Gene Blender and the human material gathered with the saucer’s Abducto Beam. These systems give players practical reasons to alternate between street-level mischief and UFO abductions.

Crypto’s flying saucer remains an important part of Destroy All Humans! 2 on PS2. It can be brought to available landing zones, used for aerial attacks, and fitted with its own destructive capabilities and defensive options. The campaign also includes Furon challenges connected to Arkvoodle, which can open further landing points and reduce unnecessary travel through the world. Whether controlling Crypto on the ground or operating the saucer above a city, the game leans into the fantasy of an invading alien who can turn ordinary human infrastructure into ammunition.

The story sends Crypto from Bay City, a San Francisco-inspired setting, to Albion, Takoshima, Tunguska, and the lunar Project Solaris. Along the way he works with the holographic Orthopox, crosses paths with agents and Soviet forces, and confronts a threat that reaches beyond the human political conflicts being parodied. Each destination recasts familiar 1960s imagery through the series’ comic science-fiction lens, supplying different missions, characters, enemies, and spaces for the player’s powers. The campaign is a sequel rather than a remake, so its plot and mechanics belong to the original PlayStation 2 and Xbox release.

Destroy All Humans! 2 also supports local multiplayer on the PlayStation 2. Two players can share the experience through split-screen cooperative play, including the story campaign and free-roam play, and can take part in competitive activities such as PK Tennis and Duel. That feature makes the PS2 version notable within the series: the same alien abilities, open-area chaos, and mission objectives can be tackled alongside another player rather than only in the single-player campaign. A later remake, Destroy All Humans! 2: Reprobed, revisited the game for newer systems, but the 2006 PS2 release is the original sixth-generation version from Pandemic Studios.